Two unique restriction endonucleases from Neisseria lactamica.
نویسندگان
چکیده
Two new site-specific endonucleases, N1a III and N1a IV, have been isolated from Neisseria lactamica. N1a III recognizes the sequence, CATG, and cleaves 3' of the sequence to produce a four base 3' extension. N1a IV recognizes the sequence, GGNNCC, and cleaves between the two N's to produce blunt ended fragments.
منابع مشابه
Genetic diversity and carriage dynamics of Neisseria lactamica in infants.
Neisseria lactamica, a harmless human commensal found predominantly in the upper respiratory tracts of infants, is closely related to Neisseria meningitidis, a pathogen of global significance. Colonization with N. lactamica may be responsible for the increase in immunity to meningococcal disease that occurs during childhood, when rates of meningococcal carriage are low. This observation has led...
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 14 5 شماره
صفحات -
تاریخ انتشار 1986